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The weekend sees the initial Wear-Tyne derby since 2024, but who will emerge victorious – Sunderland or Newcastle?
"For most of last season, it was unthinkable Sunderland rising to the top flight and challenging with Eddie Howe's Newcastle, much less being above them in the table," commented football expert Chris Sutton.
"The situation is very different now, and the way Sunderland play makes me think they've got a real chance."
He is offering predictions for all 380 Premier League games this campaign, against artificial intelligence, the public and a variety of guests.
For the upcoming matchday, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the England's esports team – the Football Association's official esports team – at the gaming title Uefa eEuro 2025 finals tournament, which is being held at Twickenham Stadium on Saturday.
The action will be streamed on Uefa's video platform, Instagram Live and short-form video channels, as well as the official Twitch channel and YouTube and the national team's Twitch.
Are you in alignment with their predictions? Feel free to submit your own predictions below.
The fan-favourite scoreline picked for each game is used in the leaderboards at the bottom of this page.
Getting the win/draw/loss right (choosing a win, draw or defeat) is worth 10 points. The exact score earns 40 points.
Ray, who represents his club side and Manchester City as well as England, is competing for the first time at the eEuros finals after successfully navigating the preliminary stage.
Eight players will fly the flag at the finals in a straight knockout, competing for a substantial cash prize and a coveted spot in the FC Pro World Championship Play-Ins, with the Danish representative Anders Vejrgang defending the title he won last year.
"I'm feeling really good for it," Ray said. "I've got a really good coach alongside me and practice has been going well.
"It is invariably an honour to play for your country. Naturally when you are younger, you fantasise about doing it as an real-life footballer, but when you go into this field and there is an chance to represent England, donning the national jersey is something incredible.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"In my opinion he is the top competitor in the world so beating him in a tournament like this just provides a massive injection of confidence."
Premier League Predictions
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
Chelsea were impressive against Arsenal at the end of November, when they earned a stalemate after being reduced to 10 men, and I was thinking here we go, they could possibly be title contenders.
However, since that game, however, they were outfought by Leeds, looked lethargic against Bournemouth and this week got beaten by Atalanta in the Champions League.
So manager Enzo Maresca is in need of a win here to return to winning ways, but it won't be easy because the Toffees are such a potent team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing at the top of their game and Everton have got a bit of form at the moment.
On form you would likely back the visitors, while the most sensible prediction would probably be a draw, but I am not going to be sensible.
The Blues have failed to given me any good cause to back them recently, but I just have a gut instinct Chelsea will win this match because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be fascinating to see what we get from Liverpool.
It was great to see for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday following all the discussion with Mohamed Salah this week.
Slot ought not to put up with that nonsense. I know Salah has been a icon for the club but at its core Slot just wants to win games and there is nothing personal in his team selection.
They changed their shape against Inter and went with a midfield diamond formation and two up top.
All the talk is going to be talking about whether Salah is back for this game, but the only way he is going to be reintegrated is if he says sorry.
Slot's focus will be on winning this game, but it is a challenging encounter.
It's fair to say it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are vulnerable at the back too.
Liverpool need to get back to stringing wins together, but I am not sure how much their efforts at the San Siro will have taken out of them.
I have whacked a couple of Brighton players in my FPL team, so they will likely do poorly - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
With the exception of their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, particularly straight after they've played in the Champions League.
The pattern suggests that tendency to continue on Sunday, and their fatigue is likely to be a key element in how this game goes because of their rivals' intensity.
It was evident how relentless Regis le Bris's side are. They dominated the Gunners, and it was amazing to watch.
Commentators talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been excellent, but Noah Sadiki, who plays in midfield with him, has also been one of the signings of the season and should be recognised too.
I am expecting this being the best game|most exciting fixture